Growth Hormone in Bone Remodeling
نویسندگان
چکیده
منابع مشابه
Growth hormone and bone.
The significance of growth hormone in the psychology of bone remodeling is now strongly recognized. It influences osteoblast function and growth in vitro as well as in vivo. Although in vivo bone resorption is also stimulated, short administration of growth hormone induces a sustained stimulation of osteoblastic function, whereas the influence on resorption probably diminishes earlier. Growth h...
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The authors report two cases of bone disorders in children with short stature, with confirmed growth hormone (GH) deficiency treated by GH supplementation. The first patient, aged 15 years, developed avascular necrosis of the femoral head and scoliosis. The second one, aged 17 years, had avascular necrosis of the femoral capital epiphysis on one side and acute slipped capital femoral epiphysis ...
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Using mice transgenic for the growth hormone gene (TGHM), we have studied the effects of a systemic elevation of growth hormone on vascular growth with the aim of investigating the role of vascular mass changes in producing hypertension. In contrast to human acromegaly or gigantism, there was no elevation of blood pressure in TGHM, but there were significant increases in vascular wall mass. In ...
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BACKGROUND Growth hormone deficiency (GHD) is associated with reduced bone mineral content and increased risk of osteoporotic fractures. Reduced peak bone mass might explain the low bone mineral density (BMD) among patients with childhood onset GHD (CO-GHD) whilst the cause of osteopenia in adult-onset GHD (AO-GHD) is not fully understood. OBJECTIVES Prospective multicentric study to asses bo...
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This study analyses the growth and the growth hormone secretion of children given various conditioning protocols before bone marrow transplantation (BMT). Twenty nine children (14 boys, 15 girls) given BMT were classified according to their conditioning protocol: total body irradiation (TBI) given as a single exposure of 10 Grays (Gy, group I, 11 cases), or 8 Gy (group II, four cases), 12 Gy gi...
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ژورنال
عنوان ژورنال: Clinical Pediatric Endocrinology
سال: 1997
ISSN: 0918-5739,1347-7358
DOI: 10.1297/cpe.6.supple10_163